Allergonil Plus Tablets

Allergonil Plus is a classical Ayurvedic formulation designed for the comprehensive management of allergic conditions, skin hypersensitivity, and respiratory imbalances.
It combines a unique blend of herbs including Bacopa (Brahmi), Shwetarisha, Aragwada (Amaltas), Jeeraka, Haridra (Turmeric), Tuvaraka, Neem, Karanja, Jayanti, Gorakmundi, and is processed in a decoction of Shirisha (Albizia lebbeck).
This formulation is Kapha-Pitta balancing, promoting immunological balance by cleansing the blood, pacifying allergic reactions, and regulating overactive immune responses. It acts at the level of Rakta, Rasa, and Pranavaha Srotas.

PHARMACOLOGICAL ACTIONS & MECHANISMS

• Anti-allergic / Mast Cell Stabilizer
  ↓ Histamine release; modulates IgE-mediated response (Albizia, Neem, Curcuma)
• Immunomodulatory
  ↑ IL-10, ↓ TNF-α, normalizes T-reg activity (Bacopa, Haridra)
• Detoxification & Liver Support (Rakta Shodhana)
  Improves hepatic clearance of metabolic allergens (Cassia, Neem)
• Antioxidant
  Scavenges ROS and reduces oxidative skin damage (Haridra, Brahmi)
• Antibacterial / Antifungal
  Active against common skin and gut pathogens (Neem, Tuvaraka)
• Anti-inflammatory
  Reduces dermal & bronchial inflammation via COX-2 inhibition
• Bronchodilator & Mucolytic
  Eases bronchospasm and clears Kapha (Shirisha, Gorakmundi)

RELEVANT RESEARCH REFERENCES

1. Gupta A et al. (2020) – Curcuma longa reduces inflammation by inhibiting NF-κB pathway in allergy models.
2. Nadkarni KM (1994) – Cassia fistula effective in dermatoses and blood disorders.
3. Sengupta R et al. (2015) – Albizia lebbeck shown to stabilize mast cells and inhibit allergic inflammation.
4. Singh D et al. (2021) – Neem extract demonstrated antifungal activity against Candida and Aspergillus strains.

CONTRAINDICATIONS & PRECAUTIONS

• Avoid in pregnancy and lactation unless prescribed
• Use with caution in individuals with severe Pitta imbalance or excess body heat
• Avoid use during acute infectious febrile conditions

 AYURVEDIC DESCRIPTION

• Rasa (Taste): Tikta (Bitter), Kashaya (Astringent), Madhura (Sweet)
• Guna (Qualities): Laghu (Light), Ruksha (Dry)
• Virya (Potency): Ushna (Hot)
• Vipaka (Post-digestive effect): Katu (Pungent)
• Effect on Doshas: Pacifies Kapha and Pitta, supports Vata in immune modulation

Key ingredients like:

• Haridra – Tridosha hara, Vishaghna, and known for potent anti-inflammatory action
• Shirisha – Krimighna, Kapha-Pitta hara, best known for anti-allergic effects
• Cassia fistula – Pitta hara, mild laxative, helps in detox and skin repair
• Neem – Tikta Rasayana, Rakta shodhaka, antifungal and antibacterial

STORAGE & PACKAGING

• Pack Size: 60 Tablets (1000 mg each)
• Packaging: Moisture-proof HDPE container or blister pack
• Storage: Store in a cool, dry place away from sunlight

 CLIMATE & REGION

• Bacopa, Haridra, Neem – Thrive in tropical humid climates (South India, Eastern Ghats)
• Tuvaraka, Karanja, Aragwada – Grown in dry deciduous forests (Maharashtra, Gujarat, MP)
• Jeeraka – Cultivated in semi-arid zones like Rajasthan and Gujarat
• Shirisha & Gorakmundi – Found along riverbanks and wetland plains (Bengal, Assam, Uttar Pradesh.